NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 001406
CAS NUMBER: 87-59-2
BASE CHEMICAL NAME: XYLIDINE,2,3-
PRIMARY NAME: 2,3-XYLIDINE
CHEMICAL FORMULA: C8H11N
STRUCTURAL FORMULA:
WLN: ZR B C
SYNONYMS:
2,3-DIMETHYLANILINE
2,3-DIMETHYLBENZENAMINE
2,3-DIMETHYLPHENYLAMINE
O-XYLIDINE
2,3-XYLYLAMINE
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTIONS: Literature: Dark brown liquid
Repository:
MOLECULAR WEIGHT: 121.18
SPECIFIC GRAVITY:
DENSITY: 0.9931 g/mL @ 20 C
MP (DEG C): <-15 C
BP (DEG C): 221-222 C
SOLUBILITIES:
WATER : 1-5 mg/mL @ 24 C (RAD)
DMSO : >=100 mg/mL @ 24 C (RAD)
95% ETHANOL : >=100 mg/mL @ 24 C (RAD)
METHANOL : Not available
ACETONE : >=100 mg/mL @ 24 C (RAD)
TOLUENE : Not available
OTHER SOLVENTS: Not available
ETHER : Soluble
VOLATILITY:
Vapor pressure:
Vapor density :
FLAMMABILITY(FLASH POINT):
The flash point for this compound is 96.6 C (206 F), and it is
combustible. Fires involving this compound can be controlled
using a dry chemical, carbon dioxide or Halon extinguisher.
UEL: Not available LEL: Not available
REACTIVITY:
This chemical reacts with strong oxidizers and hypochlorite
bleaches.
STABILITY:
This material may be sensitive to prolonged exposure to light.
OTHER PHYSICAL DATA:
Refractive Index: 1.5684 @ 20 C
pKa: 9.36
Boiling point: 106 C @ 15 mm Hg
TOXICITY
NIOSH REGISTRY NUMBER: ZE8750000
TOXICITY:
typ. dose mode specie amount unit other
LD50 orl rat 933 mg/kg
LD50 orl mus 1072 mg/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
THR: MUTATION data. MODERATE oral.
CARCINOGENICITY: Not available
MUTAGENICITY:
Mutation Data:
mma-sat 5 umol/plate
TERATOGENICITY: Not available
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Status: Reported in EPA TSCA Inventory, 1983
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Xylidines
UN/ID NUMBER: UN1711
HAZARD CLASS: 6.1 SUBSIDIARY RISK: None PACKING GROUP: II
LABELS REQUIRED: Poison
PACKAGING: PASSENGER: PKG. INSTR.: 609, Y609 MAXIMUM QUANTITY: 5 L, 1 L
CARGO : PKG. INSTR.: 611 MAXIMUM QUANTITY: 60 L
SPECIAL PROVISIONS: None
USES:
This chemical is used in the manufacture of dyes; in organic
synthesis and in the manufacture of pharmaceuticals.
COMMENTS: Not available
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
This compound may cause irritation of skin, eyes and mucous
membranes upon contact.
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS: Not available
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.
OTHER: Not available
STORAGE PRECAUTIONS:
You should protect this material from exposure to light,
and store it in a refrigerator. STORE AWAY FROM SOURCES OF IGNITION.
SPILLS AND LEAKAGE:
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then,
use absorbent paper to pick up all liquid spill material. Your contaminated
clothing and absorbent paper should be sealed in a vapor-tight plastic bag for
eventual disposal. Solvent wash all contaminated surfaces with ethanol
followed by washing with a soap and water solution. Do not reenter the
contaminated area until the Safety Officer (or other responsible person) has
verified that the area has been properly cleaned.
DISPOSAL AND WASTE TREATMENT:
Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS:
Exposure to this compound can cause local irritation of skin, eyes
and mucous membranes. Other symptoms include anoxia and cyanosis;
lung, liver and kidney damage.
FIREFIGHTING: Not available
SOURCES
SOURCES:
Occupational Health Services, Inc. Hazardline. Occupational
Health Services, Inc. New York. 1983. Listed.
Windholz, M., Ed. The Merck Index. 10th Ed. Merck and Co.
Rahway, NJ. 1983. p. 1448, #9893.
Sax, N.I. Dangerous Properties of Industrial Materials. 6th Ed.
Van Nostrand Reinhold. New York. 1984. p. 2743.
Aldrich Chemical Company. Aldrich Catalog/Handbook of Fine
Chemical. Aldrich Chemical Co., Inc. Milwaukee, WI.
1984. p. 473, #14,580-7.
Deichmann, W.B. and H.W. Gerarde. Toxicology of Drugs and
Chemicals. Academic Press. New York. 1969. p. 637.
Sittig, M. Handbook of Toxic and Hazardous Chemicals. Noyes
Publications. Park Ridge, NJ. 1981. p. 716.
Occupational Safety and Health Administration. Tentative
OSHA Listing of Confirmed and Suspected Carcinogens by
Category. Occupational Safety and Health Administration.
Washington, DC. 1979. Not listed.
Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Listed.
U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substances Inventory,
Initial Inventory. 6 Vols. U.S. Environmental Protection
Agency. Washington, D.C. 1979. Listed.
Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed.
Van Nostrand Reinhold. New York. 1981. p. 1101.
Buckingham, J., Ed. Dictionary of Organic Compounds. 5th Ed.
Chapman and Hall. New York. 1982. Vol. 2, p. 2066, #D-05525.
Weast, R.C. and M.A. Astle, Eds. CRC Handbook of Chemistry
and Physics. 63rd Ed. CRC Press, Inc. Boca Raton, FL.
1982. p. C-574, no. 15013.
Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. Microfiche Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. Quarterly
Updates. ZE8750000.
[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Section 3, p. 30.
[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. November 6, 1990.
Not listed.
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