NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 000392
CAS NUMBER: 7488-56-4
BASE CHEMICAL NAME: SELENIUMDISULFIDE
PRIMARY NAME: SELENIUM DISULFIDE
CHEMICAL FORMULA: SeS2
STRUCTURAL FORMULA:
WLN: SE S2
SYNONYMS:
SELSUN BLUE
SELSUN
SELENIUM (IV) DISULFIDE (1:2)
SELENIUM SULFIDE
NCI-C50033
EXSEL
RCRA WASTE NUMBER U205
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTIONS: LITERATURE: Bright orange powder
REPOSITORY:
MOLECULAR WEIGHT: 143.09
SPECIFIC GRAVITY:
DENSITY:
MP (DEG C): <100 C
BP (DEG C): Decomposes
SOLUBILITIES:
WATER :
DMSO :
95% ETHANOL :
METHANOL : Not available
ACETONE :
TOLUENE : Not available
OTHER SOLVENTS:
Carbon disulfide: Soluble
Ammonium sulfide: Soluble
Aqueous Reagent nitric acid: Decomposes
VOLATILITY:
Vapor pressure:
Vapor density :
FLAMMABILITY(FLASH POINT):
Flash point data are not available for this chemical. It is probably combus-
tible. Fires involving this compound can be controlled with a dry chemical,
carbon dioxide or Halon extinguisher.
UEL: Not available LEL: Not available
REACTIVITY:
STABILITY:
This chemical is stable under normal laboratory conditions.
OTHER PHYSICAL DATA:
Faint odor
TOXICITY
NIOSH REGISTRY NUMBER: VS8925000
TOXICITY:
typ. dose mode specie amount unit other
LD50 orl rat 138 mg/kg
LD50 orl mus 370 mg/kg
LDLo orl rbt 55 mg/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
THR: HIGH via oral route.
CARCINOGENICITY:
Review: IARC Cancer Review: Human Inadequate Evidence
IARC Cancer Review: Animal Inadequate Evidence
IARC: Not classifiable as a human carcinogen (Group 3) [610]
Status: EPA Carcinogen Assessment Group [610]
MUTATION DATA: Not available
TERATOGENICITY: Not available
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: Federal Register (1/19/89) and 29 CFR 1910.1000 Subpart Z
Transitional Limit: PEL-TWA 0.2 mg(Se)/m3 [610]
Final Limit: PEL-TWA 0.2 mg(Se)/m3 [610]
ACGIH: TLV-TWA 0.2 mg(Se)/m3 [610]
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Standards and Regulations: DOT-IMO: Poison B; Label: Poison
Status: Reported in EPA TSCA Inventory, 1983
Meets criteria for proposed OSHA Medical Records Rule
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Selenium disulphide
UN/ID NUMBER: UN2657
HAZARD CLASS: 6.1 SUBSIDIARY RISK: None PACKING GROUP: II
LABELS REQUIRED: Poison
PACKAGING: PASSENGER: PKG. INSTR.: 613, Y613 MAXIMUM QUANTITY: 25 kg, 1 kg
CARGO : PKG. INSTR.: 615 MAXIMUM QUANTITY: 100 kg
SPECIAL PROVISIONS: None
USES:
Treatment of seborrheic dermatitis, dandruff, eczemas, dermatomycoses and
nonspecific dermatoses.
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
This compound is a strong irritant to the skin, eyes and mucous membranes.
Slight absorption occurs after local application to normal skin, but it is
absorbed more readily on inflammed or damaged skin. Prolonged contact with
the skin may result in burns and contact dermatitis. When heated to decompo-
sition it emits very toxic fumes.
MINIMUM PROTECTIVE CLOTHING:
If Tyvek-type disposable protective clothing is not worn during
handling of this chemical, wear disposable Tyvek-type sleeves taped to
your gloves.
RECOMMENDED GLOVE MATERIALS: Not available
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.
OTHER:
Since this chemical is a known or suspected carcinogen you should contact
a physician for advice regarding the possible long term health effects and
potential recommendation for medical monitoring. Recommendations from the
physician will depend upon the specific compound, its chemical, physical and
toxicity properties, the exposure level, length of exposure, and the route
of exposure.
STORAGE PRECAUTIONS:
You should store this material in a refrigerator.
SPILLS AND LEAKAGE:
If you spill this chemical, you should dampen the solid spill material
with water,then transfer the dampened material to a suitable container. Use
absorbent paper dampened with water to pick up any remaining material. Seal
your contaminated clothing and the absorbent paper in a vapor-tight plastic
bag for eventual disposal. Wash all contaminated surfaces with a soap
and water solution. Do not reenter the contaminated area until the Safety
Officer (or other responsible person) has verified that the area has been
properly cleaned.
DISPOSAL AND WASTE TREATMENT:
Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
IMMEDIATELY call a hospital or poison control center even if no symptoms
(such as redness or irritation) develop.
IMMEDIATELY transport the victim to a hospital for treatment after
washing the affected areas.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
IMMEDIATELY call a physician and be prepared to transport the victim to a
hospital even if no symptoms (such as wheezing, coughing, shortness of breath,
or burning in the mouth, throat, or chest) develop.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
Some heavy metals are VERY TOXIC POISONS, especially if their salts are
very soluble in water (e.g., lead, chromium, mercury, bismuth, osmium, and
arsenic). IMMEDIATELY call a hospital or poison control center and locate
activated charcoal, egg whites, or milk in case the medical advisor recommends
administering one of them. Also locate Ipecac syrup or a glass of salt water
in case the medical advisor recommends inducing vomiting. Usually, this is
NOT RECOMMENDED outside of a physician's care.
If advice from a physician is not readily available and the victim is
conscious and not convulsing, give the victim a glass of activated charcoal
slurry in water or, if this is not available, a glass of milk, or beaten egg
whites and IMMEDIATELY transport victim to a hospital.
If the victim is convulsing or unconscious, do not give anything by mouth,
assure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS:
Symptoms of exposure to this compound may include dermatitis, nausea, irrita-
tion of the skin, eyes and mucous membranes, garlic odor of breath, pallor,
nervousness, depression, gastrointestinal disturbance, giddiness and kerati-
tis.
SOURCES
SOURCES:
Midwest Research Institute. MRI Report for Selenium disulfide.
Kansas City, MO. September 26, 1978.
Gosselin, R.E., H.C. Hodge, and R.P. Smith. Clinical Toxicology
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Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. Microfiche Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. Quarterly
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Windholz, M., Ed. The Merck Index. 10th Ed. Merck and Co.
Rahway, NJ. 1983. p. 1213, #8283.
Sax, N.I. Dangerous Properties of Industrial Materials. 6th Ed.
Van Nostrand Reinhold. New York. 1984. p. 2391.
International Agency for Research on Cancer, World Health
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Vol. 9, pp. 245-260.
Goodman, L.S. and A. Gilman. The Pharmacological Basis of
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American Confernece of Governmental Industrial Hygenists.
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Physical Agents in the Work Environment with Intended
Changes for 1984-85. American Conference of Governmental
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American Conference of Governmental Industrial Hygenists.
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Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed.
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and Physics. 63rd Ed. CRC Press, Inc. Boca Raton, FL.
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[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Update, p. xlvii; Section 3, p. 120.
[620] United States National Toxicology Program. Chemical Status Report.
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Not listed.
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