NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)

POTASSIUM CHLORIDE




IDENTIFIERS





CATALOG ID NUMBER: 000003

CAS NUMBER: 7447-40-7

BASE CHEMICAL NAME: POTASSIUMCHLORIDE

PRIMARY NAME: POTASSIUM CHLORIDE

CHEMICAL FORMULA: KCl

STRUCTURAL FORMULA:

WLN: .KA..G

SYNONYMS:
POTASSIUM MURIATE
POTASH MURIATE
ENSEAL KCl
CHLOROPOTASSURIL
KALCORID
KALITABS
POTAVESCENT
REKAWAN
SLOW-K-TABLETS
SPAN-K
REPONE K
CHLOROVESCENT
K-CONTIN
PETER-KAL
SALT SUBSTITUTE
POTASSIUM CHLORIDE KC





PHYSICAL CHEMICAL DATA






PHYSICAL DESCRIPTIONS: White colorless cubic crystals.

MOLECULAR WEIGHT: 74.56

SPECIFIC GRAVITY: 1.984

DENSITY:

MP (DEG C): 770 C

BP (DEG C): Sublimes at 1500 C

SOLUBILITIES:
WATER : > 100 mg/mL @ 20 C (RAD)

DMSO : < 1 mg/mL @ 20 C (RAD)

95% ETHANOL : < 1 mg/mL @ 20 C (RAD)

METHANOL : Not available

ACETONE : < 1 mg/mL @ 20 C (RAD)

TOLUENE : Not available

OTHER SOLVENTS:
Glycerin: Very soluble Alkali: Very soluble
Glycerol: 1 g/14 mL

VOLATILITY: Not available

FLAMMABILITY(FLASH POINT):
Flammability data is not available, but this compound is probably
nonflammable.

UEL: Not available LEL: Not available

REACTIVITY: Violent reaction with BrF3 (H2SO4 + KMnO4)

STABILITY: This compound is hygroscopic and should be protected from moisture.

OTHER PHYSICAL DATA:
Refractive index: 1.490 pH about 7
Hygroscopic Density of saturated aqueous solution @ 15 C = 1.172
Strong saline taste.





TOXICITY






NIOSH REGISTRY NUMBER: TS8050000

TOXICITY:

  typ. dose       mode     specie     amount       unit      other

       LDLo        orl        inf        938   mg/kg/2D

       TDLo        unk        hmn        238    mg/kg/D

       LD50        orl        rat       3020      mg/kg

       LD50        ipr        rat        660      mg/kg

       LD50        ivn        rat         39      mg/kg

       LD50        orl        mus        383      mg/kg

       LD50        ipr        mus        552      mg/kg

       LD50        ivn        mus        117      mg/kg

       LDLo        ipr        dog         85      mg/kg

       LD50        orl        gpg       2500      mg/kg

       LDLo        ipr        gpg        900      mg/kg

       LDLo        scu        gpg       2550      mg/kg

       LDLo        scu        pgn       2210      mg/kg

       LDLo        scu        frg       2120      mg/kg



AQTX/TLM96: Not available

SAX TOXICITY EVALUATION: Not available

CARCINOGENICITY: Not available

MUTAGENICITY:
mmo-sat 100 ug/Plate mma-sat 100 ug/Plate
mmo-smc 2500 mmol/L

TERATOGENICITY: Not available

STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None

OTHER TOXICITY DATA:
Skin and Eye Irritation Data:
eye-rbt 500 mg/24H SEV
Review: Toxicology Review
Status: Reported in EPA TSCA Inventory, 1980
Meets criteria for proposed OSHA Medical Records Rule





OTHER DATA (Regulatory)





PROPER SHIPPING NAME (IATA): Not restricted

UN/ID NUMBER:

HAZARD CLASS: SUBSIDIARY RISK: PACKING GROUP:

LABELS REQUIRED:

PACKAGING: PASSENGER: PKG. INSTR.: MAXIMUM QUANTITY:
CARGO : PKG. INSTR.: MAXIMUM QUANTITY:

SPECIAL PROVISIONS:

USES:
Electrolyte replenisher, a nutrient and/or dietary supplement food additive.
Also used in photography, buffer solutions, electrode cells, and as a
fertilizer, salt substitute, and laboratory reagent.

COMMENTS: Occurs in nature as the mineral sylvite or sylvine.





HANDLING PROCEDURES






ACUTE/CHRONIC HAZARDS:
Information concerning the acute hazards associated with this compound
is not available.

MINIMUM PROTECTIVE CLOTHING: Not available

RECOMMENDED GLOVE MATERIALS: Not available

RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.

OTHER: Not available

STORAGE PRECAUTIONS:
You should store this material in a refrigerator.

SPILLS AND LEAKAGE:
If you should spill this chemical, use absorbent paper to pick up
all liquid spill material. Seal the absorbent paper, as well as any
of your clothing which may be contaminated, in a vapor-tight plastic
bag for eventual disposal. Wash any surfaces you may have contaminated
with a strong soap and water solution. Do not reenter the contaminated
area until the Safety Officer (or other responsible person) has verified
that the area has been properly cleaned.

DISPOSAL AND WASTE TREATMENT: Not available





EMERGENCY PROCEDURES






SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.

INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.

EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.

INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.

SYMPTOMS:
Large doses of this chemical usually induce vomiting, so acute intoxication
by mouth is rare. If no pre-existing kidney damage, it is rapidly excreted.
Poisoning disturbs the rhythm of heart. Large doses by mouth can cause
GI irritation, purging, weakness, and circulatory disturbances.

FIREFIGHTING: Not available





SOURCES






SOURCES:
Occupational Safety and Health Administration. Tentative
OSHA Listing of Confirmed and Suspected Carcinogens by
Category. Occupational Safety and Health Administration.
Washington, DC. 1979. Not listed.

Aldrich Chemical Company. Aldrich Catalog/Handbook of Fine
Chemical. Aldrich Chemical Co., Inc. Milwaukee, WI.
1982. 20,409, p. 982.

Gosselin, R.E., H.C. Hodge, R.P. Smith and M.N. Gleason. Clinical
Toxicology of Commercial Products. 4th Ed. Williams and
Wilkins, Co. Baltimore. 1976. p. 85, #144.

Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Listed.

Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Listed.

U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substances Inventory,
Initial Inventory. 6 Vols. U.S. Environmental Protection
Agency. Washington, D.C. 1979. Listed.

Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed.
Van Nostrand Reinhold. New York. 1981. p. 847.

Sax, N.I. Dangerous Properties of Industrial Materials. 5th Ed.
Van Nostrand Reinhold. New York. 1979. p. 926.

Windholz, M., Ed. The Merck Index. 9th Ed. Merck and Co.
Rahway, NJ. 1976. p. 990, #7399.

Weast, R.C. and M.A. Astle, Eds. CRC Handbook of Chemistry
and Physics. 63rd Ed. CRC Press, Inc. Boca Raton, FL.
1982. #p240, p. B-132.

Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. Microfiche Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. Quarterly
Updates. TS8050000.

[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Not listed.

[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. November 6, 1990.
Not listed.

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