NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 001854
CAS NUMBER: 60-24-2
BASE CHEMICAL NAME: MERCAPTOETHANOL,2-
PRIMARY NAME: 2-MERCAPTOETHANOL
CHEMICAL FORMULA: C2H6OS
STRUCTURAL FORMULA: HSCH2CH2OH
WLN: SH2Q
SYNONYMS:
EMERY 5791
1-ETHANOL-2-THIOL
MONOTHIOETHYLENE GLYCOL
2-HYDROXY-1-ETHANETHIOL
2-HYDROXYETHYL MERCAPTAN
2-ME
MERCAPTOETHANOL
BETA-MERCAPTOETHANOL
MONOTHIOETHYLENEGLYCOL
2-THIOETHANOL
THIOGLYCOL
THIOMONOGLYCOL
USAF EK-4196
UN2966
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTION: LITERATURE: Water-white, mobile liquid
REPOSITORY: Clear colorless liquid
MOLECULAR WEIGHT: 78.13
SPECIFIC GRAVITY: 1.1143 @ 20/4 C [017,031,047,205]
DENSITY: Not available
MP (DEG C): -100 C [058]
BP (DEG C): 157-158 C @ 742 mm Hg (decomposes) [025,031,043]
SOLUBILITIES:
WATER : >=100 mg/mL @ 20 C (RAD)
DMSO : >=100 mg/mL @ 20 C (RAD)
95% ETHANOL : >=100 mg/mL @ 20 C (RAD)
METHANOL : Not available
ACETONE : >=100 mg/mL @ 20 C (RAD)
TOLUENE : Not available
OTHER SOLVENTS:
Alcohol: Miscible [017,031,043,205]
Ether: Miscible [017,031,043,205]
Benzene: Miscible [017,031,043,205]
Most organic solvents: Miscible [025,062]
VOLATILITY:
Vapor pressure: 1.0 mm Hg @ 20 C [043,055,062]
Vapor density : 2.69 [043,430]
FLAMMABILITY(FLASH POINT):
This chemical has a flash point of 73 C (165 F) [043,205,269,275]. It
is combustible. Fires involving this material can be controlled with a dry
chemical, carbon dioxide or Halon extinguisher.
UEL: 18% [058] LEL: 2.3% [058]
REACTIVITY:
This chemical can react with oxidizing agents. Contact with metals should
be avoided [058,269]. This compound decomposes under the influence of water
and acids [058].
STABILITY:
This chemical is moisture sensitive [058,269].
OTHER PHYSICAL DATA:
Specific gravity: 1.1168 @ 20/20 C [043,062]
Boiling point: 55 C @ 13 mm Hg [017,047]; 58 C @ 18 mm Hg [025]
Refractive index: 1.4996 @ 20 C [017,031,047,430]
Disagreeable odor [062]
Viscosity: 3.43 centipoise [062]
Sets to a glass at approximately -100 C [062]
TOXICITY
NIOSH REGISTRY NUMBER: KL5600000
TOXICITY:
typ. dose mode specie amount units other
LD50 orl rat 244 mg/kg
LD50 orl mus 190 mg/kg
LC50 ihl mus 13200 mg/m3
LD50 ipr mus 200 mg/kg
LD50 ivn mus 480 mg/kg
LD50 skn rbt 150 mg/kg
LD50 skn gpg 300 mg/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
THR: Poison by ingestion, skin contact and intraperitoneal routes. Moderately
toxic by intravenous route. A skin and severe eye irritant. Human
mutagenic data. Flammable when exposed to heat, flame or oxidizers.
CARCINOGENICITY: Not available
MUTATION DATA:
test lowest dose | test lowest dose
----------- ----------------- | ----------- -----------------
dnd-omi 10 mmol/L | dns-mus:oth 30 mmol/L
dni-rat:lvr 1 mmol/L | mnt-mus:oth 100 mg/L
TERATOGENICITY: Not available
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Skin and Eye Irritation Data:
skn-rbt 10 mg/24H open
eye-rbt 2280 mg SEV
Standards and Regulations: DOT-IMO: Poison B; Label: Poison
Status: EPA TSCA Chemical Inventory, 1986
Meets criteria for proposed OSHA Medical Records Rule
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Thioglycol
UN/ID NUMBER: UN2966
HAZARD CLASS: 6.1 SUBSIDIARY RISK: None PACKING GROUP: II
LABELS REQUIRED: Poison
PACKAGING: PASSENGER: PKG. INSTR.: 609, Y609 MAXIMUM QUANTITY: 5 L, 1 L
CARGO : PKG. INSTR.: 611 MAXIMUM QUANTITY: 60 L
SPECIAL PROVISIONS: None
USES:
This compound is used as a solvent for dyestuffs, intermediate for
producing dyestuffs, pharmaceuticals, rubber chemicals, flotation agents,
insecticides, plasticizers, water-soluble reducing agent, biochemical reagent,
PVC stabilizers, agricultural chemicals and textile auxiliary.
COMMENTS: Not available
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
This compound may be fatal if inhaled, swallowed or absorbed through skin.
When heated to decomposition it emits toxic fumes of SOx, CO and CO2 [269].
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS:
GlovES+ Expert System Glove Types For The Neat (Undiluted) Chemical:
This chemical has not been tested for permeation by Radian Corporation;
however, the GlovES+ expert system was used to extrapolate permeation test
information from compounds in the same chemical class. The GlovES+ system uses
permeation data from literature sources; therefore, extra safety margins should
be used with the estimated protection time(s). If this chemical makes direct
contact with your glove, or if a tear, puncture or hole develops, replace them
at once.
The GlovES+ expert system is a tool that can help people better manage
protection from chemicals, however this tool cannot replace sound judgment nor
make technical decisions. Our GlovES+ expert system is designed to offer
initial advice and assistance in glove selection while the final glove
selection should be made by knowledgeable individuals based on the specific
circumstances involved.
Glove Type Model Number Thickness Estimated Protection Time
Butyl rubber North B-174 0.58 mm 240 min
Nitrile Pioneer A-14 0.56 mm 240 min
PE/EVOH/PE Safety 4 4H 0.07 mm 240 min
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.
OTHER: Not available
STORAGE PRECAUTIONS:
You should store this chemical under refrigerated temperatures,
and protect it from moisture. If possible, it would be prudent to
store this compound under inert atmosphere.
SPILLS AND LEAKAGE:
If you should spill this chemical, use absorbent paper to pick up
all liquid spill material. Seal the absorbent paper, as well as any
of your clothing which may be contaminated, in a vapor-tight plastic
bag for eventual disposal. Wash any surfaces you may have contaminated
with a soap and water solution. Do not reenter the contaminated
area until the Safety Officer (or other responsible person) has verified
that the area has been properly cleaned.
DISPOSAL AND WASTE TREATMENT: Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS:
Symptoms of exposure to this compound may include irritation of the skin,
eyes, mucous membranes and respiratory tract. Eye exposure may cause redness
and pain. Inhalation may cause coughing, sore throat and shortness of
breath [058].
SOURCES
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