NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)

M-CHLOROBENZOIC ACID




IDENTIFIERS





CATALOG ID NUMBER: 001994

CAS NUMBER: 535-80-8

BASE CHEMICAL NAME: CHLOROBENZOICACID,M-

PRIMARY NAME: M-CHLOROBENZOIC ACID

CHEMICAL FORMULA: C7H5ClO2

STRUCTURAL FORMULA:

WLN: Not available

SYNONYMS:
BENZOIC ACID, 3-CHLORO-
BENZOIC ACID, M-CHLORO-
3-CHLOROBENZOIC ACID





PHYSICAL CHEMICAL DATA





PHYSICAL DESCRIPTION: LITERATURE: Crystals
REPOSITORY: Fluffy white powder

MOLECULAR WEIGHT: 156.57

SPECIFIC GRAVITY: 1.496 @ 25/4 C

DENSITY: Not available

MP (DEG C): 158 C

BP (DEG C): Sublimes

SOLUBILITIES:
WATER : <1 mg/mL @ 19.5 C (RAD)

DMSO : >=100 mg/mL @ 19.5 C (RAD)

95% ETHANOL : 10-50 mg/mL @ 19.5 C (RAD)

METHANOL : Not available

ACETONE : 50-100 mg/mL @ 19.5 C (RAD)

TOLUENE : Not available

OTHER SOLVENTS: Not available
ETHER : Soluble

VOLATILITY:
Vapor pressure: Not available
Vapor density : Not available

FLAMMABILITY(FLASH POINT):
Flash point data for this compound are not available; however, it is probably
combustible. Fires involving this material can be controlled with a dry
chemical, carbon dioxide or Halon extinguisher.

UEL: Not available LEL: Not available

REACTIVITY:
This compound is incompatible with strong oxidizing agents.

STABILITY:
This chemical is stable under normal laboratory conditions. Solutions of this
chemical should be stable for 24 hours under normal lab conditions (RAD).

OTHER PHYSICAL DATA: Not available





TOXICITY





NIOSH REGISTRY NUMBER: DG4975990

TOXICITY:

       typ. dose    mode     specie      amount     units     other

         LD50       ipr       rat         750       mg/kg


AQTX/TLM96: Not available

SAX TOXICITY EVALUATION:
THR = Not available

CARCINOGENICITY: Not available

MUTATION DATA:

      test          lowest dose      |       test          lowest dose

   -----------   -----------------   |    -----------   -----------------

   Not available                     |


TERATOGENICITY: Not available

STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None

OTHER TOXICITY DATA:
Status: Reported in EPA TSCA Inventory, 1983





OTHER DATA (Regulatory)





PROPER SHIPPING NAME (IATA): Not restricted

UN/ID NUMBER:

HAZARD CLASS: SUBSIDIARY RISK: PACKING GROUP:

LABELS REQUIRED:

PACKAGING: PASSENGER: PKG. INSTR.: MAXIMUM QUANTITY:
CARGO : PKG. INSTR.: MAXIMUM QUANTITY:

SPECIAL PROVISIONS:

USES:
Preservative for glues, paints. Intermediate in the manufacture of fungi-
cides, dyes, pharmaceutical and other organic chemicals.





HANDLING PROCEDURES





ACUTE/CHRONIC HAZARDS:
This compound may be harmful by inhalation, ingestion or skin absorption.
It is irritating to eyes, skin, mucous membranes and the upper respiratory
tract. When heated to decomposition, this compound emits toxic fumes.

MINIMUM PROTECTIVE CLOTHING: Not available

RECOMMENDED GLOVE MATERIALS:
Recommended Glove Type For Use With Neat (Undiluted) Chemicals:
Recommendations based on permeation test results, are made for handling
the neat (undiluted) chemical. If this chemical makes direct contact with
your glove, or if a tear, puncture or hole develops, replace them at once.

Suggested Glove Type(s) (RAD): No information available

RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.

STORAGE PRECAUTIONS:
You should store this chemical under refrigerated temperatures,
and keep it away from oxidizing materials.

SPILLS AND LEAKAGE:
Should a spill occur while you are handling this chemical, FIRST REMOVE
ALL SOURCES OF IGNITION, then you should dampen the solid spill material with
60-70% ethanol and transfer the dampened material to a suitable container. Use
absorbent paper dampened with 60-70% ethanol to pick up any remaining material.
Seal the absorbent paper, and any of your clothes, which may be contaminated,
in a vapor-tight plastic bag for eventual disposal. Solvent wash all contamin-
ated surfaces with 60-70% ethanol followed by washing with a soap and water
solution. Do not reenter the contaminated area until the Safety Officer (or
other responsible person) has verified that the area has been properly cleaned.

DISPOSAL AND WASTE TREATMENT:
Not available

OTHER: Not available





EMERGENCY PROCEDURES





SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.

INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.

EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.

INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.

SYMPTOMS:
Exposure to this compound may result in eye and skin irritation.





SOURCES





SOURCES:
Lenga, Robert E. The Sigma-Aldrich Library of Chemical Safety Data.
Edition 1. Sigma-Aldrich Corporation. Milwaukee, WI. 1985.
p. 375; #A.

Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. Microfiche Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. Quarterly
Updates. DG497590.

Weast, R.C., M.J. Astle, and W.H. Beyer, Eds. CRC Handbook of
Chemistry and Physics. 65th Ed. CRC Press, Inc. Boca Raton,
FL. 1984. p. C-152; #2602.

Buckingham, J., Ed. Dictionary of Organic Compounds. 5th Ed.
Chapman and Hall. New York. 1982. Vol. 1, p. 1061; #C-00733.

Windholz, M., Ed. The Merck Index. 10th Ed. Merck and Co.
Rahway, NJ. 1983. p. 298; #2093.

Weast, R.C. and M.J. Astle, Eds. CRC Handbook of Data on
Organic Compounds. CRC Press, Inc. Boca Raton, FL.
1985. Vol. 1, p. 216; #B01564.

Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed.
Van Nostrand Reinhold. New York. 1981. p. 234.

U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substances Inventory,
Initial Inventory. 6 Vols. U.S. Environmental Protection
Agency. Washington, D.C. 1979. Listed.

Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.

Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.

Aldrich Chemical Company. Aldrich Catalog/Handbook of Fine
Chemical. Aldrich Chemical Co., Inc. Milwaukee, WI.
1984. p. 240; #C2,460-4.

Occupational Safety and Health Administration. Tentative
OSHA Listing of Confirmed and Suspected Carcinogens by
Category. Occupational Safety and Health Administration.
Washington, DC. 1979. Not listed.

[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Section 3, p. 69.

[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. October 3, 1990.
Not listed.

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