NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 000520
CAS NUMBER: 319-85-7
BASE CHEMICAL NAME: BHC,B-
PRIMARY NAME: BETA-BHC
CHEMICAL FORMULA: C6H6Cl6
STRUCTURAL FORMULA:
WLN: L6TJ AG BG CG DG EG FG (BETA)
SYNONYMS:
B-BHC
BETA-BENZENEHEXACHLORIDE
BETA-HEXACHLOROCYCLOHEXANE
TRANS-ALPHA-BENZENEHEXACHLORIDE
BETA-ISOMER
1A,2B,3A,4B,5A,6B-HEXACHLOROCYCLOHEXANE
BETA-BHC
BETA-LINDANE
BETA-1,2,3,4,5,6-HEXACHLOROCYCLOHEXANE
BENZENE-CIS-HEXACHLORIDE
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTIONS: Not available
MOLECULAR WEIGHT: 290.82
SPECIFIC GRAVITY: 1.89 (19)
DENSITY:Not available
MP (DEG C): 312
BP (DEG C): Not available
SOLUBILITIES:
WATER : Not available
DMSO : Not available
95% ETHANOL : Slightly soluble.
METHANOL : Not available
ACETONE : Not available
TOLUENE : Not available
OTHER SOLVENTS:
Water: Insoluble.
Chloroform: Slightly soluble.
Benzene: Slightly soluble.
VOLATILITY : Not available
FLAMMABILITY(FLASH POINT): Not available
UEL: Not available LEL: Not available
REACTIVITY: Not available
STABILITY: This compound is stable under normal laboratory conditions.
OTHER PHYSICAL DATA: Not available
TOXICITY
NIOSH REGISTRY NUMBER: GV4375000
TOXICITY:
typ. dose mode specie amount unit other
LD50 orl rat 6000 mg/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION: THR: An experimental (+,-) carcinogen.
CARCINOGENICITY:
Tumorigenic Data:
TDLo: orl-mus 18 gm/kg/2Y-C
Review: IARC Cancer Review: Animal Limited Evidence
IARC Note: Although IARC has assigned an overall evaluation to
hexachlorocyclohexanes, it has not assigned an overall evaluation
to all substances within this group [610]
Status: NTP anticipated human carcinogen [610]
MUTATION DATA: Not available
TERATOGENICITY: Not available
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Status: Reported in EPA TSCA Inventory, 1980
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Not restricted
UN/ID NUMBER:
HAZARD CLASS: SUBSIDIARY RISK: PACKING GROUP:
LABELS REQUIRED:
PACKAGING: PASSENGER: PKG. INSTR.: MAXIMUM QUANTITY:
CARGO : PKG. INSTR.: MAXIMUM QUANTITY:
SPECIAL PROVISIONS:
USES: Insecticide.
COMMENTS: Not available
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
Highly toxic carcinogen. May cause irritation on contact.
Hazardous decomposition products.
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS:
Permeation data indicate that nitrile gloves may provide pro-
tection to contact with this compound. Nitrile over latex gloves is
recommended. However, if this chemical makes contact with your gloves,
or if a tear, hole or puncture develops, remove them at once.
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with a combination filter cartridge,
i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid
gas, SO2 and a high efficiency particulate filter).
OTHER:
Since this chemical is a known or suspected carcinogen you should contact
a physician for advice regarding the possible long term health effects and
potential recommendation for medical monitoring. Recommendations from the
physician will depend upon the specific compound, its chemical, physical and
toxicity properties, the exposure level, length of exposure, and the route
of exposure.
STORAGE PRECAUTIONS: Store at or below ambient; protect from light.
SPILLS AND LEAKAGE:
Should a spill occur while you are handling this chemical, you should
dampen the solid spill material with alcohol, then transfer the dampened
material to a suitable container. Use absorbent paper dampened with alcohol
to pick up any remaining material. Seal the absorbent paper, and any of your
clothes, which may be contaminated,in a vapor-tight plastic bag for eventual
disposal. Solvent wash all contaminated surfaces with alcohol followed by
washing with a strong soap and water solution. Do not reenter the contaminate
area until the Safety Officer (or other responsible person) has verified that
the area has been properly cleaned.
DISPOSAL AND WASTE TREATMENT:
You should dispose of all waste and contaminated materials
associated with this chemical as specified by existing local,
state and federal regulations concerning hazardous waste disposal.
It is suggested that your contaminated materials should be destroyed
by incineration in a special, high temperature ( >2000 degrees F),
chemical incinerator facility.
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
IMMEDIATELY call a physician and be prepared to transport the victim to a
hospital even if no symptoms (such as wheezing, coughing, shortness of breath,
or burning in the mouth, throat, or chest) develop.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS: Not available
FIREFIGHTING:
This compound is not very flammable but any fire involving this compound
may produce dangerous vapors. You should evacuate the area. All firefighters
should wear full-body protective clothing and use self-contained breathing
apparatuses.
You should extinguish any fires involving this chemical with a dry
chemical, carbon dioxide, foam, or halon extinguisher.
SOURCES
SOURCES:
Occupational Safety and Health Administration. Tentative
OSHA Listing of Confirmed and Suspected Carcinogens by
Category. Occupational Safety and Health Administration.
Washington, DC. 1979. Listed.
Aldrich Chemical Company. Aldrich Catalog/Handbook of Fine
Chemical. Aldrich Chemical Co., Inc. Milwaukee, WI.
1982. Not listed.
Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Listed.
Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Listed.
Steere, N.V., Ed. Handbook of Laboratory Safety. 2nd Ed.
CRC Press, Inc. Cleveland, OH. 1971. Not listed.
U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substances Inventory,
Initial Inventory. 6 Vols. U.S. Environmental Protection
Agency. Washington, D.C. 1979. Listed.
Proctor, N.H. and J.P. Hughes. Chemical Hazards of the Workplace.
J.B. Lippincott. Philadelphia. 1978. Not listed.
Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed.
Van Nostrand Reinhold. New York. 1981. p. 526
International Technical Information Institute. Toxic and
Hazardous Industrial Chemicals Safety Manual for Handling
and Disposal with Toxicity and Hazard Data. International
Technical Information Institute. 1978. Not listed.
Sax, N.I. Dangerous Properties of Industrial Materials. 5th Ed.
Van Nostrand Reinhold. New York. 1979. p. 717
Windholz, M., Ed. The Merck Index. 9th Ed. Merck and Co.
Rahway, NJ. 1976. Not listed.
Weast, R.C. and M.A. Astle, Eds. CRC Handbook of Chemistry
and Physics. 63rd Ed. CRC Press, Inc. Boca Raton, FL.
1982. p. c-248, 5538
Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic
Effects of Chemical Substances. DHEW (NIOSH) Publication
No. 79-100. National Institute for Occupational Safety
and Health. Cincinnati, OH. 1979. GV4375000
[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Section 3, p. 64.
[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. October 3, 1990.
Not listed.
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