NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 001032
CAS NUMBER: 1825-21-4
BASE CHEMICAL NAME: PENTACHLOROANISOLE
PRIMARY NAME: PENTACHLOROANISOLE
CHEMICAL FORMULA: C7H3Cl5O
STRUCTURAL FORMULA: Not printable
WLN: GR BG CG DG EG FO1
SYNONYMS:
2,3,4,5,6-PENTACHLOROANISOLE
PENTACHLOROMETHOXYBENZENE
METHYL PENTACHLOROPHENATE
METHYL PENTACHLOROPHENYL ESTER
NCI-C56520
PENTACHLOROPHENYL METHYL ETHER
ANISOLE, 2,3,4,5,6-PENTACHLORO-
BENZENE, PENTACHLOROMETHOXY-
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTION: LITERATURE: Needles
REPOSITORY: White crystals
MOLECULAR WEIGHT: 280.35
SPECIFIC GRAVITY: Not available
DENSITY: Not available
MP (DEG C): 108-109 C
BP (DEG C): Not available
SOLUBILITIES:
WATER : <1 mg/mL @ 25 C (RAD)
DMSO : 50-100 mg/mL @ 16 C (RAD)
95% ETHANOL : 50-100 mg/mL @ 16 C (RAD)
METHANOL : Not available
ACETONE : 50-100 mg/mL @ 16 C (RAD)
TOLUENE : Not available
OTHER SOLVENTS: Not available
VOLATILITY:
Vapor pressure: Not available
Vapor density : Not available
FLAMMABILITY(FLASH POINT):
Flash point data for this chemical are not available; however, it is
probably combustible. Fires involving this material can be controlled with
a dry chemical, carbon dioxide or Halon extinguisher.
UEL: Not available LEL: Not available
REACTIVITY: Not available
STABILITY:
This chemical is stable under normal laboratory conditions.
OTHER PHYSICAL DATA: Not available
TOXICITY
NIOSH REGISTRY NUMBER: BZ8820000
TOXICITY:
typ. dose mode specie amount units other
LDLo orl rat 500 mg/kg
LD50 orl mus 318 mg/kg
LD50 ipr mus 281 mg/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
THR: Not available
CARCINOGENICITY:
Status: NTP Carcinogenesis Studies; on test (two year studies), April 1990
MUTATION DATA: See RTECS printout for most current data
test lowest dose | test lowest dose
----------- ----------------- | ----------- -----------------
mmo-sat 3333 ug/plate | mmo-sat 3333 ug/plate
mma-mus:lym 75 mg/L |
TERATOGENICITY: See RTECS printout for most current data
Reproductive Effects Data:
TDLo: orl-rat 7420 mg/kg (23W pre/1-22D preg)
TDLo: orl-rat 724 mg/kg (23W pre/1-22D preg)
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Status: EPA TSCA Test Submission (TSCATS) Data Base, April 1990
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Not restricted
UN/ID NUMBER:
HAZARD CLASS: SUBSIDIARY RISK: PACKING GROUP:
LABELS REQUIRED:
PACKAGING: PASSENGER: PKG. INSTR.: MAXIMUM QUANTITY:
CARGO : PKG. INSTR.: MAXIMUM QUANTITY:
SPECIAL PROVISIONS:
USES: Not available
COMMENTS: Not available
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
Information concerning acute hazards of this chemical is not available.
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS:
Permeation Test Results For The Neat (Undiluted) Chemical:
The permeation test results for the neat (undiluted) chemical are given
below. The breakthrough times of this chemical are given for each glove type
tested. The table is a presentation of actual test results, not specific
recommendations or suggestions. Avoid glove types which exhibit breakthrough
times of less than the anticipated task time plus an adequate safety factor.
If this chemical makes direct contact with your glove, or if a tear, puncture
or hole develops, replace them at once.
Glove Type Model Number Thickness Breakthrough Time
No information available
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.
OTHER: Not available
STORAGE PRECAUTIONS:
You should store this material under ambient temperatures.
SPILLS AND LEAKAGE:
Should a spill occur while you are handling this chemical, FIRST REMOVE
ALL SOURCES OF IGNITION, then you should dampen the solid spill material with
60-70% ethanol and transfer the dampened material to a suitable container. Use
absorbent paper dampened with 60-70% ethanol to pick up any remaining material.
Seal the absorbent paper, and any of your clothes, which may be contaminated,
in a vapor-tight plastic bag for eventual disposal. Solvent wash all contamin-
ated surfaces with 60-70% ethanol followed by washing with a soap and water
solution. Do not reenter the contaminated area until the Safety Officer (or
other responsible person) has verified that the area has been properly cleaned.
DISPOSAL AND WASTE TREATMENT: Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS:
Information concerning symptoms of exposure to this chemical is not
available.
SOURCES
SOURCES:
[015] Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. On-line Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. BZ8820000.
October 5, 1990.
[080] U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substances Inventory,
Initial Inventory. 6 Vols. U.S. Environmental Protection
Agency. Washington, D.C. 1979. Not listed.
[110] Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
[120] Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Section 3, p. 93.
[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. November 6, 1990.
Listed.
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