NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 002227
CAS NUMBER: 110-69-0
BASE CHEMICAL NAME: BUTANALOXIME
PRIMARY NAME: BUTANAL OXIME
CHEMICAL FORMULA: C4H9NO
STRUCTURAL FORMULA: HON=CHCH2CH2CH3
WLN: QNU4
SYNONYMS:
N-BUTYRALDEHYDE OXIME
N-BUTYRALDOXIME
BUTYRALDOXIME
BUTYRALDEHYDE OXIME
BUTYLALDOXIME
BUTANALOXIME
EXKIN 1
EXKIN NO. 1 ANTI-SKINNING AGENT
SKINO #1
TROYKYD ANTI-SKIN BTO
UN 2840
USAF AM-6
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTION: LITERATURE: Colorless liquid
REPOSITORY: Clear colorless liquid
MOLECULAR WEIGHT: 87.14
SPECIFIC GRAVITY: 0.923 [043,107]
DENSITY: Not available
MP (DEG C): -29.5 C [043,107]
BP (DEG C): 152 C [043,107]
SOLUBILITIES:
WATER : <1 mg/mL @ 20 C (RAD)
DMSO : >=100 mg/mL @ 20 C (RAD)
95% ETHANOL : >=100 mg/mL @ 20 C (RAD)
METHANOL : Not available
ACETONE : >=100 mg/mL @ 20 C (RAD)
TOLUENE : Not available
OTHER SOLVENTS: Not available
VOLATILITY:
Vapor pressure: Not available
Vapor density : 3.01 [043,107]
FLAMMABILITY(FLASH POINT):
This chemical has a flash point of 57.8 C (136 F) [043,107]. It is
combustible. Fires involving this material can be controlled with a dry
chemical, carbon dioxide or Halon extinguisher. A water spray may also
be used [058].
UEL: Not available LEL: Not available
REACTIVITY:
This chemical is incompatible with oxidizing materials [043,058]. It
is also incompatible with metallic impurities [043]. It may react with
strong acids [058].
STABILITY:
This chemical is highly explosive during vacuum distillation [043].
NMR stability screening indicates that solutions of this chemical in acetone
are stable for at least 24 hours (RAD).
OTHER PHYSICAL DATA:
Evaporation rate: slower than ether [058]
100% volatile by volume [058]
TOXICITY
NIOSH REGISTRY NUMBER: ES3500000
TOXICITY:
typ. dose mode specie amount units other
LD50 ipr mus 200 mg/kg
LDLo orl rbt 100 mg/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
THR: A poison by intraperitoneal route.
CARCINOGENICITY: Not available
MUTATION DATA:
test lowest dose | test lowest dose
----------- ----------------- | ----------- -----------------
Not available |
TERATOGENICITY: Not available
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: None
ACGIH: None
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Standards and Regulations: DOT-IMO: Flammable or Combustible liquid;
Label: Flammable liquid
Status: EPA TSCA Chemical Inventory, 1986
EPA TSCA Section 8(e) Status Report 8EHQ-1185-0573
EPA TSCA Test Submission (TSCATS) Data Base, March 1988
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Butyraldoxime
UN/ID NUMBER: UN2840
HAZARD CLASS: 3 SUBSIDIARY RISK: None PACKING GROUP: III
LABELS REQUIRED: Flammable liquid
PACKAGING: PASSENGER: PKG. INSTR.: 309, Y309 MAXIMUM QUANTITY: 60 L, 10 L
CARGO : PKG. INSTR.: 310 MAXIMUM QUANTITY: 220 L
SPECIAL PROVISIONS: None
USES:
This compound is used as an anti-skinning agent.
COMMENTS: Not available
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
This compound may cause irritation of the skin, eyes and nose [058,107].
When heated to decomposition it emits toxic fumes of nitrogen oxides [043].
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS:
GlovES+ Expert System Glove Types For The Neat (Undiluted) Chemical:
This chemical has not been tested for permeation by Radian Corporation;
however, the GlovES+ expert system was used to extrapolate permeation test
information from compounds in the same chemical class. The GlovES+ system uses
permeation data from literature sources; therefore, extra safety margins should
be used with the estimated protection time(s). If this chemical makes direct
contact with your glove, or if a tear, puncture or hole develops, replace them
at once.
The GlovES+ expert system is a tool that can help people better manage
protection from chemicals, however this tool cannot replace sound judgment nor
make technical decisions. Our GlovES+ expert system is designed to offer
initial advice and assistance in glove selection while the final glove
selection should be made by knowledgeable individuals based on the specific
circumstances involved.
Glove Type Model Number Thickness Estimated Protection Time
PVA Edmont 25-555 Unknown 240 min
Viton North F-091 0.25 mm 240 min
PE/EVOH/PE Safety 4 4H 0.07 mm 240 min
RECOMMENDED RESPIRATOR:
Where the neat test chemical is weighed and diluted, wear a NIOSH-
approved half face respirator equipped with an organic vapor/acid gas
cartridge (specific for organic vapors, HCl, acid gas and SO2) with a
dust/mist filter.
OTHER: Not available
STORAGE PRECAUTIONS:
You should store this chemical under refrigerated temperatures,
and keep it away from oxidizing materials.
SPILLS AND LEAKAGE:
If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then,
use absorbent paper to pick up all liquid spill material. Your contaminated
clothing and absorbent paper should be sealed in a vapor-tight plastic bag for
eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol
followed by washing with a soap and water solution. Do not reenter the
contaminated area until the Safety Officer (or other responsible person) has
verified that the area has been properly cleaned.
DISPOSAL AND WASTE TREATMENT: Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS:
Symptoms of exposure to this compound include irritation of the skin,
eyes and nose; extrasystoles, dermatitis, drowsiness, dyspnea and palpitations
[107]. Prolonged contact may result in moderate irritation. It may interfere
with the oxidation of alcohol in the body resulting in the formation of in-
creased amounts of acetaldehyde, blotchy red marks, red eyes, tiredness and
visible veins [058].
SOURCES
SOURCES:
[015] Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic Effects
of Chemical Substances. On-line Ed. National Institute for
Occupational Safety and Health. Cincinnati, OH. ES3500000.
January 24, 1989.
[043] Sax, N.I. and Richard J. Lewis, Sr. Dangerous Properties of Industrial
Materials. 7th Ed. Van Nostrand Reinhold. New York. 1989.
Vol. II, p. 658, #BSU500.
[058] Information Handling Services. Material Safety Data Sheets
Service. Microfiche Ed. Bimonthly Updates. February/
March 1989. #5810-016, C-01.
[082] U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substance Inventory: 1985
Edition. 5 Vols. U.S. Environmental Protection Agency.
Washington, D.C. January 1986. Listed.
[107] Occupational Health Services, Inc. Hazardline. Occupational
Health Services, Inc. New York. August 18, 1988.
[110] Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Listed.
[120] Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Section 3, p. 46.
[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. October 3, 1990.
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