NTP CHEMICAL REPOSITORY (RADIAN CORPORATION, AUGUST 29, 1991)
IDENTIFIERS
CATALOG ID NUMBER: 001057
CAS NUMBER: 102-81-8
BASE CHEMICAL NAME: DIBUTYLAMINOETHANOL,2-N-
PRIMARY NAME: 2-N-DIBUTYLAMINOETHANOL
CHEMICAL FORMULA: C10H23NO
STRUCTURAL FORMULA:
WLN: Q2N4&4
SYNONYMS:
2-DI-n-BUTYLAMINOETHANOL
2-(DI-n-BUTYLAMINO)ETHANOL
DIBUTYLAMINOTHANOL
BETA-N-DIBUTYLAMINOETHYL ALCOHOL
N,N-DIBUTYLETHANOLAMINE
N,N-DIBUTYL-N-(2-HYDROXYETHYL)AMINE
BU2AE
N,N-DI-N-BUTYLAMINOETHANOL
PHYSICAL CHEMICAL DATA
PHYSICAL DESCRIPTIONS: Clear colorless liquid
MOLECULAR WEIGHT: 173.34
SPECIFIC GRAVITY: 0.85
DENSITY: Not available
MP (DEG C): Not available
BP (DEG C): 224-232 C
SOLUBILITIES:
WATER : <1 mg/mL @ 18 C (RAD)
DMSO : >=100 mg/mL @ 18 C (RAD)
95% ETHANOL : >=100 mg/mL @ 18 C (RAD)
METHANOL : Not available
ACETONE : >=100 mg/mL @ 18 C (RAD)
TOLUENE : Not available
OTHER SOLVENTS: Not available
VOLATILITY :
Vapor density : 6.0
FLAMMABILITY(FLASH POINT):
The flash point for this chemical is 99 C (210 F); it is combustible.
Fires involving this compound should be controlled with a dry chemical, carbon
dioxide or halon extinguisher.
UEL: Not available LEL: Not available
REACTIVITY: Not available
STABILITY: This compound should be stable under normal laboratory conditions.
OTHER PHYSICAL DATA:
Vapor density: 6.0
Faint amine-like odor
TOXICITY
NIOSH REGISTRY NUMBER: KK3850000
TOXICITY:
typ. dose mode specie amount unit other
LD50 orl rat 1070 mg/kg
LD50 ipr rat 144 mg/kg
LD50 ipr mus 52 mg/kg
LD50 skn rbt 1680 mg/kg
AQTX/TLM96: Not available
SAX TOXICITY EVALUATION:
THR=MOD via oral and dermal routes. Can be absorbed by skin in toxic
quantities.
CARCINOGENICITY: Not available
MUTATION DATA: Not available
TERATOGENICITY: Not available
STANDARDS, REGULATIONS & RECOMMENDATIONS:
OSHA: Federal Register (1/19/89)
Final Limit: PEL-TWA 2 ppm [610]
ACGIH: TLV-TWA 2 ppm (skin) [610]
NIOSH Criteria Document: None
NFPA Hazard Rating: Health (H): None
Flammability (F): None
Reactivity (R): None
OTHER TOXICITY DATA:
Skin and Eye Irritation Data:
skn-rbt 1 mg/24H
skn-rbt 500 mg open SEV
eye-rbt 20 mg/24H SEV
Status: Reported in EPA TSCA Inventory, 1980
"NIOSH Manual of Analytical Methods" Vol 4 270, Vol 5 S140
OTHER DATA (Regulatory)
PROPER SHIPPING NAME (IATA): Dibutylaminoethanol
UN/ID NUMBER: UN2873
HAZARD CLASS: 6.1 SUBSIDIARY RISK: None PACKING GROUP: III
LABELS REQUIRED: Keep away from food
PACKAGING: PASSENGER: PKG. INSTR.: 611, Y611 MAXIMUM QUANTITY: 60 L, 2 L
CARGO : PKG. INSTR.: 618 MAXIMUM QUANTITY: 220 L
SPECIAL PROVISIONS: None
USES: Synthesis
HANDLING PROCEDURES
ACUTE/CHRONIC HAZARDS:
This chemical is toxic by ingestion and by skin absorption.
MINIMUM PROTECTIVE CLOTHING: Not available
RECOMMENDED GLOVE MATERIALS: Not available
RECOMMENDED RESPIRATOR:
When working with this chemical, wear a NIOSH-approved full face
positive pressure supplied-air respirator or a self-contained breathing
apparatus (SCBA). [651]
OTHER: Not available
STORAGE PRECAUTIONS:
You should store this material in a refrigerator.
SPILLS AND LEAKAGE:
If you spill this chemical, use absorbent paper to pick up all liquid
spill material. Your contaminated clothing and absorbent paper should be
sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all
contaminated surfaces with alcohol followed by washing with a strong soap and
water solution. Do not reenter the contaminated area until the Safety Officer
(or other responsible person) has verified that the area has been properly
cleaned.
DISPOSAL AND WASTE TREATMENT: Not available
EMERGENCY PROCEDURES
SKIN CONTACT:
IMMEDIATELY flood affected skin with water while removing and isolating
all contaminated clothing. Gently wash all affected skin areas thoroughly
with soap and water.
If symptoms such as redness or irritation develop, IMMEDIATELY call a
physician and be prepared to transport the victim to a hospital for treatment.
INHALATION:
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air.
If symptoms (such as wheezing, coughing, shortness of breath, or burning in
the mouth, throat, or chest) develop, call a physician and be prepared to
transport the victim to a hospital.
Provide proper respiratory protection to rescuers entering an unknown
atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA)
should be used; if not available, use a level of protection greater than or
equal to that advised under Respirator Recommendation.
EYE CONTACT:
First check the victim for contact lenses and remove if present. Flush
victim's eyes with water or normal saline solution for 20 to 30 minutes while
simultaneously calling a hospital or poison control center.
Do not put any ointments, oils, or medication in the victim's eyes without
specific instructions from a physician.
IMMEDIATELY transport the victim after flushing eyes to a hospital even if
no symptoms (such as redness or irritation) develop.
INGESTION:
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing,
give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a
hospital or poison control center. Be prepared to transport the victim to a
hospital if advised by a physician.
If the victim is convulsing or unconscious, do not give anything by mouth,
ensure that the victim's airway is open and lay the victim on his/her side with
the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport
the victim to a hospital.
SYMPTOMS: Information on the symptoms associated with this compound is not ava
FIREFIGHTING: Not available
SOURCES
SOURCES:
Occupational Safety and Health Administration. Tentative
OSHA Listing of Confirmed and Suspected Carcinogens by
Category. Occupational Safety and Health Administration.
Washington, DC. 1979. Not listed.
Aldrich Chemical Company. Aldrich Catalog/Handbook of Fine
Chemicals. Aldrich Chemical Co., Inc. Milwaukee, WI.
1980. Not listed.
Oak Ridge National Laboratory. Environmental Teratogen Information
Center (ETIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
Oak Ridge National Laboratory. Environmental Mutagen Information
Center (EMIC), Bibliographic Data Base. Oak Ridge National
Laboratory. Oak Ridge, TN. Not listed.
Steere, N.V., Ed. Handbook of Laboratory Safety. 2nd Ed.
CRC Press, Inc. Cleveland, OH. 1971. Not listed.
U.S. Environmental Protection Agency, Office of Toxic Substances.
Toxic Substances Control Act Chemical Substances Inventory,
Initial Inventory. 6 Vols. U.S. Environmental Protection
Agency. Washington, D.C. 1979. Listed.
Proctor, N.H. and J.P. Hughes. Chemical Hazards of the Workplace.
J.B. Lippincott. Philadelphia. 1978. Not listed.
Hawley, G.G., Ed. The Condensed Chemical Dictionary. 10th Ed.
Van Nostrand Reinhold. New York. 1981. pp. 328.
International Technical Information Institute. Toxic and
Hazardous Industrial Chemicals Safety Manual for Handling
and Disposal with Toxicity and Hazard Data. International
Technical Information Institute. 1978. Not listed.
Sax, N.I. Dangerous Properties of Industrial Materials. 4th Ed.
Van Nostrand Reinhold. New York. 1975. pp. 550-551.
Windholz, M., Ed. The Merck Index. 9th Ed. Merck and Co.
Rahway, NJ. 1976. Not listed.
Weast, R.C. and M.A. Astle, Eds. CRC Handbook of Chemistry
and Physics. 60th Ed. CRC Press, Inc. Boca Raton, FL.
1982. Not listed.
Lewis, R.J., Sr. and R.L. Tatken, Eds. Registry of Toxic
Effects of Chemical Substances. DHEW (NIOSH) Publication
No. 79-100. National Institute for Occupational Safety
and Health. Cincinnati, OH. 1979. KK3850000.
[610] Clansky, Kenneth B., Ed. Suspect Chemicals Sourcebook: A Guide to
Industrial Chemicals Covered Under Major Federal Regulatory and
Advisory Programs. Roytech Publications, Inc. Burlingame, CA.
1990. Section 3, p. 36.
[620] United States National Toxicology Program. Chemical Status Report.
NTP Chemtrack System. Research Triangle Park, NC. November 6, 1990.
Not listed.
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